Description

Vasopressin, 1-(Tetrahydro-4-Mercapto-2H-Pyran-4-Acetic Acid)-2-(o-Ethyl-D-Tyrosine)-4-L-Valine-8-L-Arginine- is a high-purity synthetic peptide analog of the endogenous hormone vasopressin, designed for advanced pharmaceutical research and development. This compound is engineered to offer enhanced stability and specific receptor binding profiles, making it a critical tool for studying and modulating vasopressin pathways. It is primarily utilized by pharmaceutical companies, biotechnology research institutions, and academic laboratories focused on endocrinology, cardiovascular research, and novel therapeutic discovery.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material for quality control and analytical method development in drug manufacturing.
• Biomedical Research: Used in in vitro and in vivo studies to investigate the physiological roles of vasopressin receptors (V1a, V1b, V2).
• Drug Discovery & Development: Acts as a key intermediate or active pharmaceutical ingredient (API) in the development of novel therapeutics for conditions like diabetes insipidus, septic shock, and bleeding disorders.
• Biochemical Assays: Employed in high-throughput screening (HTS) and receptor binding assays to identify and characterize new modulators.
• Academic & Clinical Studies: Supports fundamental research into water-electrolyte balance, blood pressure regulation, and social behavior.
• Peptide Chemistry Research: Used as a model compound for studying peptide stability, modification, and structure-activity relationships (SAR).

Basic Information

Product Name	Vasopressin, 1-(Tetrahydro-4-Mercapto-2H-Pyran-4-Acetic Acid)-2-(o-Ethyl-D-Tyrosine)-4-L-Valine-8-L-Arginine-
CAS No.	133073-75-3
Molecular Formula	C52H74N14O13S2
Molecular Weight	1151.36 g/mol
Synonyms	Desmopressin Acetate Impurity; [1-(β-Mercapto-β,β-cyclopentamethylenepropionic acid), 2-(O-ethyl-D-tyrosine), 4-valine, 8-arginine]vasopressin; (1-Deamino-4-valine, 8-D-arginine)vasopressin analog; d(CH2)5[D-Tyr(Et)2,Val4,Arg8]VP; V1a Vasopressin Receptor Antagonist; [d(CH2)5¹,Tyr(Me)²,Arg⁸]vasopressin (common research alias); Mercapto-cyclopentamethylenepropionyl¹-O-ethyl-D-Tyr²-Val⁴-Arg⁸-vasopressin
EINECS	Contact for details

Quality Control

Our Vasopressin analog is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. We provide full traceability and Certificates of Analysis (COA) that detail all critical quality attributes. Production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 95.0% (Total Peptide Content)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	5.0% - 12.0%
Amino Acid Analysis	Within ± 10% of theoretical values

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.