Description

2-[2-(5-Bromo-1H-Indol-3-Yl)Ethyl]-3-[3-(1-Methylethoxy)Phenyl]-4-(3H)-Quinazolinone is a high-purity, complex heterocyclic organic compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical pharmacological intermediate or reference standard for the synthesis of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies to optimize drug-like properties.
• Reference Standard: Serves as an analytical standard for quality control and method development in API (Active Pharmaceutical Ingredient) manufacturing.
• Biochemical Tool Compound: Potential use in vitro and in vivo studies to investigate enzyme inhibition or receptor modulation.
• Academic Research: Employed in university laboratories for advanced studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2-[2-(5-Bromo-1H-Indol-3-Yl)Ethyl]-3-[3-(1-Methylethoxy)Phenyl]-4-(3H)-Quinazolinone
CAS No.	133040-77-4
Molecular Formula	C27H24BrN3O2
Molecular Weight	502.40 g/mol
Synonyms	5-Bromo-3-[2-[3-(3-isopropoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]ethyl]-1H-indole; 2-[2-(5-Bromo-1H-indol-3-yl)ethyl]-3-(3-isopropoxyphenyl)quinazolin-4(3H)-one; 133040-77-4; 3-(3-Isopropoxyphenyl)-2-[2-(5-bromo-1H-indol-3-yl)ethyl]-4(3H)-quinazolinone; Quinazolinone derivative, BRD-K4477 (research code); 5-Bromotryptamine quinazolinone derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request. We adhere to cGMP principles where applicable to support our clients in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.