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Ookinete Antigen P25, Plasmodium CAS NO 132965-94-7


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CAS No.:132965-94-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Ookinete Antigen P25, Plasmodium is a specific protein antigen derived from the ookinete stage of the *Plasmodium* parasite, the causative agent of malaria. This high-purity biological reagent is critical for research and development in parasitology and vaccine studies. It is primarily utilized by biotechnology firms, academic research institutions, and diagnostic manufacturers engaged in malaria research, immunology, and the development of novel therapeutic and diagnostic solutions.

Application

  • Malaria Vaccine Research: A key target antigen for the development of transmission-blocking vaccines (TBVs) aimed at interrupting the parasite's life cycle in the mosquito vector.
  • Immunoassay Development: Used as a coating antigen or standard in ELISA and other immunoassays to detect and quantify anti-P25 antibodies in serum samples.
  • Antibody Production: Serves as an immunogen for generating monoclonal and polyclonal antibodies specific to the *Plasmodium* ookinete stage.
  • Parasite Biology Studies: Essential for fundamental research into the molecular biology, immunogenicity, and invasion mechanisms of the *Plasmodium* ookinete.
  • Diagnostic Kit Manufacturing: Incorporated into lateral flow assays or other point-of-care diagnostic tools for malaria surveillance and epidemiological studies.
  • Quality Control Reference: Acts as a reference standard for the quality control of other malaria-related biological products and assays.

Basic Information

Product Name Ookinete Antigen P25, Plasmodium
CAS No. 132965-94-7
Molecular Formula Contact for details
Molecular Weight Contact for details
Synonyms P25 Ookinete Antigen; Plasmodium P25 Protein; Pfs25 Antigen (P. falciparum); Pvs25 Antigen (P. vivax); Transmission-Blocking Vaccine Antigen P25; Ookinete Surface Protein P25; Malaria Ookinete Antigen; Circumsporozoite and TRAP-related Protein (CTRP)
EINECS Contact for details

Quality Control

Our Ookinete Antigen P25 is produced and tested under stringent conditions to ensure high batch-to-batch consistency and biological activity. Each lot undergoes comprehensive analytical characterization. Certificates of Analysis (COA) detailing purity, identity, and functional activity are provided and available upon request, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Avoid repeated freeze-thaw cycles. Aliquot upon receipt for single-use applications to maintain optimal activity.

Specification

Item Specification
Appearance White to off-white lyophilized powder
Identification (SDS-PAGE/Western Blot) Consistent with recombinant P25 antigen
Purity (SDS-PAGE) > 90%
Protein Content (BCA/Bradford) > 95% of total weight
Endotoxin Level (LAL) < 1.0 EU/µg
Biological Activity (ELISA/IFA) Reactive with specific monoclonal antibodies
Solubility Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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