Description

N(Alpha)-Biotinyl-Neuropeptide Y CAS NO 132964-49-9 is a biotinylated derivative of the important neuropeptide Y (NPY), designed for high-affinity detection and isolation applications. This modification is critical for researchers requiring sensitive and specific targeting in complex biological matrices. This product is primarily utilized by life science researchers and diagnostic developers in the fields of neuroscience, endocrinology, and molecular biology for advanced assay development.

Application

• Biomarker Research & Detection: Used as a critical reagent in immunoassays (e.g., ELISA, Western Blot) for the sensitive detection and quantification of NPY and its receptors.
• Affinity Purification & Pull-Down Assays: Leverages the strong biotin-streptavidin interaction to isolate NPY-binding proteins, receptors, or complexes from cell lysates and tissue samples.
• Neuroscience & Receptor Studies: Essential for studying NPY signaling pathways, receptor-ligand interactions, and the role of NPY in appetite regulation, stress response, and cardiovascular function.
• Diagnostic Kit Development: Serves as a standardized component in the development of in-vitro diagnostic (IVD) kits and research-use-only (RUO) kits targeting the NPY system.
• Cell Imaging & Localization: Conjugated with fluorescent tags via the biotin handle for visualizing NPY receptor distribution and internalization in cellular models.
• High-Throughput Screening (HTS): Employed in screening campaigns to identify novel agonists or antagonists for NPY receptors in drug discovery.

Basic Information

Product Name	N(Alpha)-Biotinyl-Neuropeptide Y
CAS No.	132964-49-9
Molecular Formula	C192H290N56O57S
Molecular Weight	4252.8 g/mol
Synonyms	Biotin-NPY; Biotinylated Neuropeptide Y; NPY-Biotin; Neuropeptide Y (Biotinylated); Biotinyl-Neuropeptide Y; N-α-Biotinyl-NPY; Biotin-LC-NPY; [Biotinyl]Neuropeptide Y
EINECS	Contact for details

Quality Control

Our N(Alpha)-Biotinyl-Neuropeptide Y is manufactured under strict quality protocols to ensure batch-to-batch consistency and high biological activity. Each lot is characterized using advanced analytical techniques including HPLC for purity assessment and Mass Spectrometry (MS) for identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, peptide content, and performance data is provided with every shipment to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Biological Activity	Confirmed by binding assay (Data on COA)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.