Description

α-Cgrp (30-37) (Rat) is a synthetic peptide fragment corresponding to amino acid residues 30-37 of the rat Calcitonin Gene-Related Peptide (CGRP). This high-purity peptide is a critical research tool for studying the structure-activity relationships and biological functions of CGRP, a potent neuropeptide involved in vasodilation and pain transmission. It is essential for researchers and developers in neuroscience, cardiovascular research, and pharmaceutical discovery who require reliable, well-characterized biochemicals for assay development and mechanistic studies.

Application

• Neuroscience Research: Used as a reference standard or active agent in studies investigating the role of CGRP in migraine, neurogenic inflammation, and nociception.
• Cardiovascular Studies: Employed in vasodilation assays and research on blood pressure regulation due to CGRP's potent vasodilatory effects.
• Pharmaceutical Screening: Serves as a key ligand or competitor in high-throughput screening (HTS) campaigns to identify novel CGRP receptor antagonists or modulators.
• Biochemical Assay Development: Acts as a critical component in developing and validating ELISA, RIA, or other immunoassays specific to CGRP or its fragments.
• Structure-Activity Relationship (SAR) Studies: Provides a defined peptide sequence for modifying and testing to understand the core bioactive region of the full-length CGRP protein.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental biological studies and grant-supported projects.

Basic Information

Item	Detail
Product Name	α-Cgrp (30-37) (Rat)
CAS No.	132917-49-8
Molecular Formula	C41H68N14O11
Molecular Weight	933.1 g/mol
Synonyms	Calcitonin Gene-Related Peptide (30-37), rat; α-CGRP (30-37), rat; CGRP-(30-37); H-Val-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-OH; CGRP Fragment (30-37); Rat α-Calcitonin Gene-Related Peptide (30-37); Neuropeptide Fragment
EINECS	Contact for details

Quality Control

Every batch of α-Cgrp (30-37) (Rat) is manufactured and analyzed under strict quality protocols. Our products undergo rigorous testing, including HPLC for purity verification and MS for identity confirmation, to ensure they meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and chromatographic data is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Assay (Peptide Content)	≥ 80%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.