Description

α-Cgrp (32-37) (Rat) is a synthetic peptide fragment corresponding to amino acids 32-37 of the rat Calcitonin Gene-Related Peptide (CGRP). This high-purity biochemical is a critical research tool for studying the structure, function, and receptor interactions of CGRP, a potent neuropeptide involved in vasodilation and pain signaling. It is essential for neuroscientists, pharmacologists, and research institutions focused on cardiovascular biology, migraine research, and neuropharmacology. CAS No. 132917-48-7.

Application

• Neuroscience Research: Used as a reference standard and active agent in studies investigating the role of CGRP in the central and peripheral nervous systems.
• Pharmacological Assays: Serves as a key ligand in receptor binding studies, competitive inhibition assays, and functional activity tests for CGRP receptor antagonists.
• Cardiovascular Studies: Employed in research models to examine CGRP's vasodilatory effects and its implications in blood pressure regulation and vascular diseases.
• Migraine & Pain Research: A vital component in preclinical research aimed at understanding CGRP-mediated pain pathways and developing novel analgesic therapeutics.
• Biochemical Standardization: Acts as a purity standard for quality control in the production and analysis of related CGRP peptides and analogs.
• Antibody Production & Validation: Utilized as an immunogen or as a coating antigen for the development and specificity testing of anti-CGRP antibodies.

Basic Information

Product Name	α-Cgrp (32-37) (Rat)
CAS No.	132917-48-7
Molecular Formula	C33H55N11O9S
Molecular Weight	781.93 g/mol
Synonyms	Calcitonin Gene-Related Peptide (32-37) (rat); α-CGRP (32-37), rat; CGRP32-37 (rat); H-Val-Tyr-Val-Asp-His-Lys-OH; CGRP Fragment 32-37; Rat α-CGRP (32-37); CGRPrat (32-37)
EINECS	Contact for details

Quality Control

Every batch of α-Cgrp (32-37) (Rat) is manufactured and analyzed under stringent quality systems to ensure identity, purity, and consistency for critical research applications. Our standard grade meets high-purity specifications typical for research peptides, with comprehensive analysis via HPLC and Mass Spectrometry. A detailed Certificate of Analysis (COA) providing batch-specific data for purity, amino acid analysis, and solvent content is supplied with each product.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Amino Acid Composition	Conforms to theoretical values (±10%)
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80% (by weight)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.