Description

Proline, 1-(2-Propenyl)-, Methyl Ester (9Ci) is a specialized proline derivative, a chiral non-proteinogenic amino acid ester. This compound serves as a versatile and high-value building block in advanced organic synthesis, particularly for introducing constrained proline-like motifs. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, where its unique structure can influence biological activity and molecular conformation.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially protease inhibitors and other bioactive molecules.
• Peptidomimetics & Constrained Peptide Design: Used to incorporate modified proline residues into peptides to enhance stability, bioavailability, and receptor selectivity.
• Agrochemical Synthesis: Serves as a precursor in creating novel herbicides, fungicides, or plant growth regulators with specific stereochemical requirements.
• Asymmetric Catalysis: Potential use as a ligand or precursor for chiral catalysts in stereoselective chemical transformations.
• Biochemical Research: Employed in studies of enzyme inhibition, protein-protein interactions, and structure-activity relationships (SAR).
• Fine Chemical Production: A building block for synthesizing complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	Proline, 1-(2-Propenyl)-, Methyl Ester (9Ci)
CAS No.	132910-67-9
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	1-Allyl-L-proline methyl ester; Methyl 1-(2-propenyl)-L-prolinate; L-Proline, 1-(2-propenyl)-, methyl ester; (S)-1-Allyl-pyrrolidine-2-carboxylic acid methyl ester; 1-Allylproline methyl ester; Allyl-L-proline methyl ester; Methyl 1-allyl-L-prolinate
EINECS	Contact for details

Quality Control

Our Proline, 1-(2-Propenyl)-, Methyl Ester (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent chiral integrity. Standard quality parameters include assay (HPLC), enantiomeric excess (Chiral HPLC), and identification (IR, NMR). A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.