Description

Glutaryl-Phenylalanyl-Alanyl-Alanyl-Phenylalanine 4-Methoxynaphthylamide is a specialized synthetic peptide derivative designed for advanced biochemical research and development. This compound serves as a critical substrate and tool in enzymatic studies, particularly for investigating protease activity and specificity. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require high-purity, well-characterized biochemical tools for drug discovery and assay development.

Application

• Protease Substrate: Used as a selective fluorogenic or chromogenic substrate for the study and characterization of various proteolytic enzymes, including serine and cysteine proteases.
• Biochemical Assay Development: A key component in the design and optimization of high-throughput screening (HTS) assays for drug discovery programs targeting protease-related diseases.
• Enzyme Kinetics Research: Employed to determine kinetic parameters (Km, Vmax, kcat) and inhibition constants (Ki) for evaluating potential therapeutic inhibitors.
• Diagnostic Reagent Manufacturing: Incorporated into diagnostic kits and reagents for the detection and quantification of specific protease activities in clinical samples.
• Academic & Industrial R&D: Supports fundamental research in biochemistry, cell biology, and medicinal chemistry within university laboratories and corporate R&D centers.

Basic Information

Product Name	Glutaryl-Phenylalanyl-Alanyl-Alanyl-Phenylalanine 4-Methoxynaphthylamide
CAS No.	132806-29-2
Molecular Formula	C43H51N7O9
Molecular Weight	809.92 g/mol
Synonyms	Glutaryl-Phe-Ala-Ala-Phe-4-Methoxy-2-Naphthylamide; Glutaryl-F-A-A-F-4MβNA; Protease Substrate IV; G-Phe-Ala-Ala-Phe-4MNA; 4-Methoxynaphthylamide Derivative of Glutaryl-Phe-Ala-Ala-Phe; Fluorogenic Peptide Substrate; Chromogenic Peptide Substrate; N-Glutaryl-L-phenylalanyl-L-alanyl-L-alanyl-L-phenylalanine 4-methoxy-2-naphthylamide
EINECS	Contact for details

Quality Control

Every batch of Glutaryl-Phenylalanyl-Alanyl-Alanyl-Phenylalanine 4-Methoxynaphthylamide is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and performance consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay purity, HPLC profile, and optical rotation. Our quality system is designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (Mass Spectrometry)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.