Description

Elugent(Tm) Detergent is a high-performance, non-ionic detergent specifically designed for the solubilization and purification of membrane proteins. Its core value proposition lies in its ability to effectively extract and stabilize integral membrane proteins while maintaining their native structure and function for downstream analysis. This makes it an indispensable reagent for researchers and process developers in structural biology, drug discovery, and biopharmaceutical manufacturing. Industries requiring advanced protein characterization and purification, such as pharmaceutical R&D, academic research, and contract research organizations, are the primary users of this critical material.

Application

• Membrane Protein Solubilization: Primary application for extracting integral membrane proteins from lipid bilayers for biochemical and biophysical studies.
• Structural Biology: Essential for preparing stable samples of membrane proteins for techniques like X-ray crystallography, cryo-electron microscopy (cryo-EM), and NMR spectroscopy.
• Drug Discovery & Development: Used in high-throughput screening (HTS) assays and target validation studies involving G-protein-coupled receptors (GPCRs), ion channels, and transporters.
• Protein Purification: Facilitates the purification of recombinant membrane proteins expressed in various host systems by maintaining solubility throughout chromatography steps.
• Functional Assays: Enables the reconstitution of purified membrane proteins into liposomes or other membrane-mimetic systems to study transport activity, ligand binding, and enzyme kinetics.
• Vaccine Development: Potential use in the extraction and presentation of viral membrane antigens.

Basic Information

Product Name	Elugent(Tm) Detergent
CAS No.	132778-08-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Elugent; Elugent Detergent; n-Dodecyl-β-D-maltopyranoside (DDM) analog; Lauryl maltose neopentyl glycol (LMNG); Glycol-diosgenin (GDN); Maltose-neopentyl glycol (MNG) detergent; Non-ionic maltoside detergent; Membrane protein detergent
EINECS	Contact for details

Quality Control

Our Elugent(Tm) Detergent is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, consistent performance, and lot-to-lot reproducibility critical for sensitive research applications. Certificates of Analysis (COA) detailing purity, critical micelle concentration (CMC), and functional performance data are provided with every shipment. We adhere to relevant quality standards suitable for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store at room temperature (15-25°C) in a dry, well-ventilated area. Keep away from heat and incompatible materials. For long-term stability, consider storage at 2-8°C. Allow the product to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms
Purity (HPLC)	≥ 95%
Critical Micelle Concentration (CMC)	Reported
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, buffers
Functional Performance	Maintains membrane protein activity

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.