Description

H-Leu-Ala-Pro-Oh is a high-purity tripeptide derivative, specifically the C-terminal carboxylic acid form of the Leu-Ala-Pro sequence. This compound is a valuable building block in peptide synthesis and pharmaceutical research, offering precise structural control for developing novel bioactive molecules. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers focused on peptide-based drug discovery and advanced biochemical applications.

Application

• Pharmaceutical Intermediate: A key building block for the solid-phase and solution-phase synthesis of longer, more complex therapeutic peptides.
• Biochemical Research: Used as a standard or substrate in enzymatic studies and proteomics research to investigate peptide metabolism and interactions.
• Drug Discovery: Serves as a core structural motif in the design and screening of peptide libraries for new drug candidates targeting various diseases.
• Cosmeceutical Development: Incorporated into the research of bioactive peptides for advanced skincare formulations aimed at anti-aging or skin repair.
• Academic & Industrial R&D: Employed in universities and corporate labs for fundamental studies on peptide structure-activity relationships (SAR) and stability.

Basic Information

Product Name	H-Leu-Ala-Pro-Oh
CAS No.	132548-09-5
Molecular Formula	C14H25N3O4
Molecular Weight	299.37 g/mol
Synonyms	L-Leucyl-L-alanyl-L-proline; Leu-Ala-Pro; L-Leu-L-Ala-L-Pro-OH; H-Leu-Ala-Pro-OH; Tripeptide Leu-Ala-Pro; (2S)-1-[(2S)-2-[[(2S)-2-Amino-4-methylpentanoyl]amino]propanoyl]pyrrolidine-2-carboxylic acid; L-Leucine-L-alanine-L-proline; N-(N-L-Leucyl-L-alanyl)-L-proline
EINECS	Contact for details

Quality Control

Our H-Leu-Ala-Pro-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material tailored to specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.