Description

2-(Trifluoromethyl)-1H-Indole-3-Acetic Acid is a high-value fluorinated indole derivative, a key building block in advanced organic synthesis. Its trifluoromethyl group and indole-acetic acid scaffold make it a critical intermediate for developing novel compounds with enhanced biological activity and metabolic stability. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating new active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially non-steroidal anti-inflammatory agents, enzyme inhibitors, and receptor modulators.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators, leveraging the bioactivity of the indole ring system.
• Fluorine Chemistry: Serves as a versatile synthon for introducing the trifluoromethyl group into complex molecules, a common strategy in medicinal chemistry to improve lipophilicity and bioavailability.
• Biochemical Research: Employed as a tool compound or a starting material for synthesizing probes to study enzyme mechanisms and biological pathways.
• Material Science: Potential building block for specialty polymers, liquid crystals, or organic electronic materials due to its aromatic and fluorinated structure.

Basic Information

Product Name	2-(Trifluoromethyl)-1H-Indole-3-Acetic Acid
CAS No.	132502-93-3
Molecular Formula	C11H8F3NO2
Molecular Weight	243.18 g/mol
Synonyms	2-(Trifluoromethyl)indole-3-acetic acid; 3-Indoleacetic acid, 2-(trifluoromethyl)-; 2-(Trifluoromethyl)-1H-indole-3-acetic acid; α-(2-Trifluoromethyl-1H-indol-3-yl)acetic acid; 2-(Trifluoromethyl)indol-3-ylacetic acid; 2-(Trifluoromethyl)-3-indoleacetic acid; 2-Trifluoromethylindole-3-acetic acid
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)-1H-Indole-3-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.