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Lhrh, His(6)-n-Et-Pronh2(9)- CAS NO 132461-43-9
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CAS No.:132461-43-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Lhrh, His(6)-n-Et-Pronh2(9)- is a synthetic peptide analog of Luteinizing Hormone-Releasing Hormone (LHRH) with specific modifications at the histidine and proline residues. This engineered compound is significant for its enhanced stability and targeted biological activity, making it a valuable tool in advanced research and development. It is primarily needed by the pharmaceutical and biotechnology sectors for applications in endocrinology research, drug discovery, and the development of novel therapeutic agents.
Application
- Pharmaceutical Research & Development: As a key intermediate or reference standard in the development of hormone-based therapeutics and diagnostic agents.
- Endocrinology Studies: For investigating the structure-activity relationships (SAR) of LHRH analogs and their interaction with receptors.
- Bioconjugation & Probe Development: Serving as a modified peptide scaffold for creating labeled probes used in biochemical assays and imaging studies.
- Academic & Institutional Research: Utilized in university and institutional labs for fundamental studies in peptide chemistry and neuroendocrinology.
- Preclinical Studies: Evaluation of pharmacokinetic and pharmacodynamic properties of novel LHRH analog candidates.
Basic Information
| Product Name | Lhrh, His(6)-n-Et-Pronh2(9)- |
| CAS No. | 132461-43-9 |
| Molecular Formula | Contact for details |
| Molecular Weight | Contact for details |
| Synonyms | LHRH analog, His(6)-N-ethyl-Pro-NH2(9)-LHRH; Modified Luteinizing Hormone-Releasing Hormone; LHRH (6-His(N-Et), 9-Pro-NH2); Gonadorelin analog; pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 derivative; Synthetic LHRH peptide; LHRH agonist/antagonist intermediate |
| EINECS | Contact for details |
Quality Control
Our Lhrh, His(6)-n-Et-Pronh2(9)- is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets exacting research-grade specifications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a dry environment. For long-term storage, consider desiccated conditions.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC/MS) | Conforms |
| Purity (HPLC) | ≥ 95.0% |
| Single Impurity (HPLC) | ≤ 1.0% |
| Water Content (KF) | ≤ 5.0% |
| Peptide Content | ≥ 80.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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