Description

Lesopitron is a selective 5-HT1A receptor agonist with the CAS registry number 132449-46-8. This compound is of significant interest in pharmaceutical research and development due to its potential anxiolytic and antidepressant properties. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel central nervous system (CNS) therapeutics.

Application

• Pharmaceutical Research & Development: As a key intermediate or active pharmaceutical ingredient (API) in preclinical and clinical studies for anxiety and depression disorders.
• Neuropharmacology Studies: Used as a reference standard or tool compound to investigate the role of 5-HT1A receptors in neurological pathways and behaviors.
• Drug Discovery Programs: Serves as a lead compound or scaffold for the synthesis of new chemical entities targeting serotonin receptors.
• Analytical Reference Standard: Employed in method development and quality control (QC) testing within analytical laboratories for identification and assay purposes.
• Academic Research: Utilized in university and institutional labs for fundamental studies on receptor pharmacology and signal transduction.

Basic Information

Product Name	Lesopitron
CAS No.	132449-46-8
Molecular Formula	C17H23N3O2
Molecular Weight	301.39 g/mol
Synonyms	Lesopitron; 8-[4-(4-Phenyl-1-piperazinyl)butyl]-8-azaspiro[4.5]decane-7,9-dione; DU-125530; EMD-49980; EMD 49980; DU 125530; 8-[4-(4-Phenylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione
EINECS	Contact for details

Quality Control

Our Lesopitron is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity determination by HPLC, and control of related substances and residual solvents. A Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.