Description

3-Propylproline is a non-proteinogenic proline derivative characterized by a propyl side chain at the 3-position of the pyrrolidine ring. This structural modification makes it a valuable chiral building block and intermediate in advanced organic synthesis, particularly for the development of pharmaceuticals and bioactive compounds. It is primarily utilized by research institutions and chemical companies engaged in peptide mimetic design, medicinal chemistry, and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptidomimetics Research: Used in the design and construction of peptide analogs and mimetics to modulate biological activity and stability.
• Medicinal Chemistry: Serves as a constrained scaffold in structure-activity relationship (SAR) studies and lead optimization.
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block in stereoselective catalytic reactions.
• Biochemical Research: Utilized in studies probing enzyme-substrate interactions, particularly those involving proline-specific enzymes.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	3-Propylproline
CAS No.	132437-60-6
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	3-Propylpyrrolidine-2-carboxylic acid; (S)-3-Propylproline; (2S)-3-Propylpyrrolidine-2-carboxylic acid; 3-n-Propylproline; L-3-Propylproline; Proline, 3-propyl-; 132437-60-6; 3-Propyl-2-pyrrolidinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Propylproline is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.