Description

tert-Butyloxycarbonyl-Alanyl-Dehydrophenylalanyl-Glycyl-Dehydrophenylalanyl-Alanyl-Methoxy is a synthetic, protected peptide sequence containing dehydroamino acid residues. This compound is a critical building block in advanced peptide synthesis, offering precise control over molecular structure and stereochemistry. It is primarily utilized by research institutions and pharmaceutical developers working on novel therapeutic peptides, peptidomimetics, and bioactive molecular probes.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Peptidomimetic Research: Used to introduce conformational constraints and dehydroamino acid motifs into peptide backbones for structure-activity relationship (SAR) studies.
• Biochemical Tool Development: Employed in the creation of enzyme inhibitors, receptor ligands, and other bioactive probes for biochemical and pharmacological research.
• Solid-Phase Peptide Synthesis (SPPS): Acts as a protected fragment for segment condensation or as a specialized monomer in Fmoc/t-Boc synthesis strategies.
• Academic & Industrial R&D: Fundamental material for exploring new synthetic methodologies and peptide modifications in both academic and industrial laboratory settings.

Basic Information

Item	Details
Product Name	tert-Butyloxycarbonyl-Alanyl-Dehydrophenylalanyl-Glycyl-Dehydrophenylalanyl-Alanyl-Methoxy
CAS No.	132413-71-9
Molecular Formula	C33H41N5O8
Molecular Weight	635.71 g/mol
Synonyms	Boc-A-δPhe-G-δPhe-A-OMe; Boc-Ala-δPhe-Gly-δPhe-Ala-OMe; N-(tert-Butoxycarbonyl)alanyl-α,β-dehydrophenylalanylglycyl-α,β-dehydrophenylalanylalanyl methyl ester; t-Boc-Ala-(Z)-δPhe-Gly-(Z)-δPhe-Ala-OMe; Protected pentapeptide with dehydro-Phe; Dehydrophenylalanine-containing peptide building block
EINECS	Contact for details

Quality Control

Every batch of our peptide building blocks is produced and tested under strict quality management protocols. We provide comprehensive analytical data to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing results from HPLC, MS, and NMR are supplied with each shipment, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the material should be handled in a low-humidity environment and sealed under inert gas (argon or nitrogen) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.