Description

1,2,3,4-Tetrahydro-1,3-Dimethyl-Beta,2,4-Trioxo-6-(Phenylamino)-5-Pyrimidinepropanenitrile is a specialized heterocyclic organic compound with a complex pyrimidine-based structure, serving as a key advanced intermediate in fine chemical synthesis. Its molecular architecture makes it valuable for constructing more complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and high-performance materials. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate and scale novel synthetic pathways.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific receptor-binding activities.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic core for bioactivity.
• Organic Synthesis & Process Chemistry: Serves as a versatile precursor for constructing complex nitrogen-containing heterocycles in academic and industrial research laboratories.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials or ligands for catalytic systems due to its conjugated system and functional groups.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	1,2,3,4-Tetrahydro-1,3-Dimethyl-Beta,2,4-Trioxo-6-(Phenylamino)-5-Pyrimidinepropanenitrile
CAS No.	132373-29-6
Molecular Formula	C₁₆H₁₆N₄O₃
Molecular Weight	312.33 g/mol
Synonyms	6-(Phenylamino)-1,3-dimethyl-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinepropanenitrile; 5-Pyrimidinepropanenitrile, 1,2,3,4-tetrahydro-1,3-dimethyl-β,2,4-trioxo-6-(phenylamino)-; 132373-29-6; 6-Anilino-1,3-dimethyl-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinepropionitrile; Tetrahydrodimethyltrioxophenylaminopyrimidinepropanenitrile
EINECS	Contact for details

Quality Control

Our production of 1,2,3,4-Tetrahydro-1,3-Dimethyl-Beta,2,4-Trioxo-6-(Phenylamino)-5-Pyrimidinepropanenitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all critical specifications are provided with every shipment. We support compliance with cGMP standards where required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.