Description

6-Chloro-9-Cyclobutyl-9H-Purine is a high-purity, advanced pharmaceutical intermediate with the CAS number 132332-65-1. This compound is a key building block in the synthesis of novel nucleoside analogs and purine derivatives, offering significant value in medicinal chemistry research and development. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing antiviral, anticancer, and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel adenosine receptor antagonists and other purine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Antiviral Drug Development: Used in the research and synthesis of potential antiviral compounds targeting viral polymerases.
• Oncology Research: Employed as a building block for creating purine analogs investigated for their antiproliferative and chemotherapeutic properties.
• Biochemical Tool Compound: Utilized in biochemical assays to study enzyme inhibition, particularly kinases and phosphodiesterases.
• Fine Chemical Synthesis: Acts as a specialized intermediate for custom synthesis and contract manufacturing of complex organic molecules.

Basic Information

Product Name	6-Chloro-9-Cyclobutyl-9H-Purine
CAS No.	132332-65-1
Molecular Formula	C9H9ClN4
Molecular Weight	208.65 g/mol
Synonyms	9-Cyclobutyl-6-chloro-9H-purine; 6-Chloro-9-cyclobutylpurine; 6-Chloro-9-cyclobutyl-7H-purine; 6-Chloro-9-cyclobutyl-9H-purine; Purine, 6-chloro-9-cyclobutyl-; 132332-65-1; 6-Chlor-9-cyclobutyl-9H-purin; 6-Chloro-9-cyclobutylpurine
EINECS	Contact for details

Quality Control

Our 6-Chloro-9-Cyclobutyl-9H-Purine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.