Description

Fmoc-Lys(Boc)-Osu CAS NO 132307-50-7 is a high-purity, protected amino acid derivative widely used as a critical building block in solid-phase peptide synthesis (SPPS). Its value lies in providing orthogonal protection for the lysine side chain, enabling the controlled synthesis of complex peptides and peptide libraries. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key reagent for the controlled, sequential addition of lysine residues in automated and manual peptide synthesis.
• Therapeutic Peptide Development: Used in the research and production of peptide-based drugs targeting metabolic disorders, oncology, and infectious diseases.
• Peptide Library Construction: Enables the generation of diverse peptide libraries for high-throughput screening in drug discovery and epitope mapping.
• Bioconjugation and Labeling: Serves as a versatile intermediate for attaching peptides to other molecules, surfaces, or fluorescent probes via its active ester group.
• Antibody-Drug Conjugate (ADC) Research: Employed in the synthesis of peptide linkers that connect cytotoxic payloads to monoclonal antibodies.
• Academic and Industrial R&D: A fundamental reagent in university and corporate laboratories for investigating protein-protein interactions and structure-activity relationships.

Basic Information

Product Name	Fmoc-Lys(Boc)-Osu
CAS No.	132307-50-7
Molecular Formula	C31H38N4O8
Molecular Weight	594.66 g/mol
Synonyms	Fmoc-Lys(Boc)-OSu; Nα-Fmoc-Nε-Boc-L-lysine N-succinimidyl ester; Nα-(9-Fluorenylmethoxycarbonyl)-Nε-(tert-butoxycarbonyl)-L-lysine N-hydroxysuccinimide ester; Fmoc-Lys(Boc)-ONSu; Fmoc-Lys(Boc)-NHS ester; (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonylamino)-6-((tert-butoxycarbonyl)amino)hexanoic acid 2,5-dioxopyrrolidin-1-yl ester; Nα-Fmoc-Nε-Boc-L-lysine succinimidyl ester
EINECS	Contact for details

Quality Control

Our Fmoc-Lys(Boc)-Osu is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing assay, chiral purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This material is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a dry environment before opening to prevent condensation. For long-term stability, store under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.5%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 0.5%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.