Description

Cyclic(3-1)-1-(Carboxymethyl)Prolyl-Phenylalanyl-Histidinamide is a synthetic cyclic peptide derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or active pharmaceutical ingredient (API) for investigating novel therapeutic pathways, particularly in areas requiring high specificity and biological activity. It is primarily utilized by research institutions, biotechnology firms, and pharmaceutical companies engaged in the discovery and synthesis of peptide-based drugs, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex peptide-based Active Pharmaceutical Ingredients (APIs).
• Biochemical Research: Used as a reference standard or probe in studying enzyme-substrate interactions, receptor binding, and signal transduction pathways.
• Drug Discovery: Acts as a core structure for the development of novel therapeutic agents targeting specific diseases.
• Diagnostic Development: Employed in the creation of labeled compounds for imaging and diagnostic assays.
• Peptide Library Synthesis: Utilized in combinatorial chemistry to generate diverse peptide libraries for high-throughput screening.

Basic Information

Product Name	Cyclic(3-1)-1-(Carboxymethyl)Prolyl-Phenylalanyl-Histidinamide
CAS No.	132235-85-9
Molecular Formula	C₂₄H₂₉N₇O₆
Molecular Weight	511.54 g/mol
Synonyms	Cyclo(CM-Pro-Phe-His); c(CM-Pro-Phe-His); 1-(Carboxymethyl)-L-prolyl-L-phenylalanyl-L-histidinamide cyclic (3-1)-peptide; Cyclic CM-Pro-Phe-His amide; Histidinamide, L-phenylalanyl-1-(carboxymethyl)-L-prolyl-, cyclic (3-1)-peptide; CAS 132235-85-9; L-Histidinamide, L-phenylalanyl-1-(carboxymethyl)-L-prolyl-, cyclic (3-1)-peptide
EINECS	Contact for details

Quality Control

Our Cyclic(3-1)-1-(Carboxymethyl)Prolyl-Phenylalanyl-Histidinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for residual solvents and moisture content, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.