Description

Pancreatic Polypeptide (Rana Temporaria) is a bioactive peptide hormone originally isolated from the European common frog, *Rana temporaria*. This specific polypeptide is of significant interest in comparative endocrinology and metabolic research due to its structural and functional differences from mammalian pancreatic polypeptides. It serves as a critical research tool for scientists and pharmaceutical developers investigating peptide evolution, receptor interactions, and potential therapeutic applications. Key users include academic research institutions, biotechnology companies, and pharmaceutical R&D departments focused on endocrinology and metabolic disorders.

Application

• Biomedical Research: Fundamental studies on the structure, function, and evolution of peptide hormones in non-mammalian vertebrates.
• Receptor Binding Assays: Used as a ligand to characterize and study pancreatic polypeptide (PP) receptor subtypes and their signaling pathways.
• Comparative Endocrinology: Investigating the role of pancreatic polypeptide in amphibian physiology, including feeding behavior and metabolism.
• Pharmaceutical R&D: Serves as a reference standard or starting material in the development of novel peptide-based therapeutics or diagnostic tools.
• Academic Teaching: Used in advanced biochemistry and physiology courses to demonstrate peptide hormone diversity and action.

Basic Information

Product Name	Pancreatic Polypeptide (Rana Temporaria)
CAS No.	132187-74-7
Molecular Formula	C185H285N55O55S2 (Approximate, for 36-amino acid form)
Molecular Weight	~4200 Da (Approximate)
Synonyms	Rana Temporaria Pancreatic Polypeptide; Frog Pancreatic Polypeptide; PP (Rana temporaria); Avian Pancreatic Polypeptide-like Peptide (Frog); APP (Rana temporaria); Pancreatic Polypeptide Frog; PPY (Rana temporaria); Polypeptide Y (Frog)
EINECS	Contact for details

Quality Control

Our Pancreatic Polypeptide (Rana Temporaria) is produced and handled under strict quality protocols suitable for research applications. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing key parameters such as purity by HPLC, peptide content, and amino acid analysis. We adhere to high standards of quality assurance to support reliable and reproducible scientific research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider storing under an inert atmosphere or with desiccant.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Composition	Conforms to theoretical sequence
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.