Description

n-Acetyl-Cholera Toxin (50-64)-3-Amide is a chemically modified, active fragment of the cholera toxin protein. This compound is critical for advanced biochemical research and pharmaceutical development, particularly in the study of G-protein signaling pathways and cellular intoxication mechanisms. It is primarily utilized by research institutions, diagnostic manufacturers, and biopharmaceutical companies engaged in vaccine development, toxin research, and the creation of novel therapeutic agents.

Application

• Biochemical Research: A key tool for studying ADP-ribosylation factors and the mechanism of action of bacterial toxins.
• Vaccine Development: Used in the research and production of conjugate vaccines and toxoids.
• Diagnostic Reagents: Serves as a critical antigen or standard in immunoassays and toxin detection kits.
• Cell Biology Studies: Employed to investigate G-protein coupled receptor (GPCR) pathways and intracellular signaling cascades.
• Neuroscience Research: Utilized in studies of neuronal signaling and the effects of neuroactive agents.
• Pharmaceutical Reference Standard: Acts as a high-purity standard for quality control in biopharmaceutical manufacturing.

Basic Information

Product Name	n-Acetyl-Cholera Toxin (50-64)-3-Amide
CAS No.	132177-90-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cholera Toxin Fragment (50-64), N-Acetyl Amide; CTX (50-64) Amide; Acetylated Cholera Toxin Peptide; Cholera Toxin Subunit Fragment; N-Acetyl-CTX(50-64)-NH2; Vibrio cholerae Toxin Derivative; Research Grade Cholera Toxin Peptide; G-Protein Modulating Peptide
EINECS	Contact for details

Quality Control

Our n-Acetyl-Cholera Toxin (50-64)-3-Amide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep desiccated under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO, and aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.