Description

Suc-Phe-Glu-Pro-Ile-Pro-Glu-Glu-Tyr(So3H)-Leu-D-Glu-Oh CAS NO 131791-98-5 is a synthetic, sulfated tyrosine-containing peptide derivative. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a specific substrate or inhibitor for studying enzyme activity, particularly for kinases and phosphatases involved in signal transduction pathways. It is primarily utilized by research institutions and pharmaceutical development companies focused on metabolic regulation, inflammation, and oncology target validation.

Application

• Biochemical Research: Used as a specific substrate for studying the kinetics and inhibition profiles of tyrosine kinases and sulfatases.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the discovery and development of targeted therapies for cancer and inflammatory diseases.
• Enzyme Characterization: Employed in assays to characterize the specificity and activity of enzymes that recognize sulfated tyrosine residues.
• Signal Transduction Studies: A critical tool for investigating phosphorylation/dephosphorylation cascades and intracellular signaling mechanisms.
• Diagnostic Reagent Manufacturing: Can be incorporated into diagnostic kits for detecting specific enzyme activities in clinical samples.

Basic Information

Product Name	Suc-Phe-Glu-Pro-Ile-Pro-Glu-Glu-Tyr(So3H)-Leu-D-Glu-Oh
CAS No.	131791-98-5
Molecular Formula	C68H94N12O28S
Molecular Weight	1559.6 g/mol
Synonyms	Suc-F-E-P-I-P-E-E-Y(SO3H)-L-E-OH; Succinyl-Phe-Glu-Pro-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-D-Glu-OH; Suc-F-E-P-I-P-E-E-Y(SO3)-L-E-OH; Tyrosine-sulfated peptide substrate; Suc-FEPIPEEY(sulfo)-L-E-OH; pSulfo-Tyr peptide; Suc-Phe-Glu-Pro-Ile-Pro-Glu-Glu-O-sulfo-Tyr-Leu-D-Glu-OH
EINECS	Contact for details

Quality Control

Our Suc-Phe-Glu-Pro-Ile-Pro-Glu-Glu-Tyr(So3H)-Leu-D-Glu-Oh is produced under stringent conditions to ensure batch-to-batch consistency and high purity for research applications. All materials are subjected to rigorous analytical testing, including HPLC for purity and MS for identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.