Description

1-(4-Methoxybenzyl)-2,4-Dioxo-1,2,3,4-Tetrahydro-5-Pyrimidinecarbonitrile is a high-purity, advanced pharmaceutical intermediate with a distinct pyrimidinecarbonitrile core structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, antiviral agents, and enzyme inhibitors.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with specific modes of action.
• Chemical Synthesis: Used in organic synthesis for constructing complex pyrimidine and dihydropyrimidine derivatives, which are privileged scaffolds in medicinal chemistry.
• Academic & R&D: Employed in university and corporate research laboratories for method development, structure-activity relationship (SAR) studies, and exploring new chemical entities.
• Material Science: Potential applications in the development of specialty chemicals and functional materials due to its unique electronic properties.

Basic Information

Product Name	1-(4-Methoxybenzyl)-2,4-Dioxo-1,2,3,4-Tetrahydro-5-Pyrimidinecarbonitrile
CAS No.	131699-05-3
Molecular Formula	C₁₃H₁₁N₃O₃
Molecular Weight	257.25 g/mol
Synonyms	5-Cyano-1-(4-methoxybenzyl)dihydrouracil; 1-(4-Methoxybenzyl)-5-cyanodihydrouracil; 1-(4-Methoxybenzyl)dihydro-5-cyanouracil; 1-(p-Methoxybenzyl)-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinecarbonitrile; 5-Pyrimidinecarbonitrile, 1-[(4-methoxyphenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydro-; Dihydrouracil-5-carbonitrile, 1-(4-methoxybenzyl)-; CAS 131699-05-3
EINECS	Contact for details

Quality Control

Our 1-(4-Methoxybenzyl)-2,4-Dioxo-1,2,3,4-Tetrahydro-5-Pyrimidinecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.