Description

Insulin Like Growth Factor I (1-27)-Gly-Gly-Gly-Gly-(38-70) is a synthetic peptide fragment of Insulin-like Growth Factor 1 (IGF-1), a critical protein involved in cellular growth and development. This engineered sequence is designed for high-purity research and development applications, offering a specific tool for studying IGF-1 receptor interactions and signaling pathways. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical developers focused on metabolic research, cell culture studies, and therapeutic peptide discovery.

Application

• Biomedical Research: A key reagent for investigating the structure-activity relationship (SAR) of IGF-1 and its receptor binding mechanisms.
• Cell Culture & Proliferation Studies: Used in in vitro assays to study the effects of IGF-1 fragments on cell growth, differentiation, and survival.
• Pharmaceutical Development: Serves as a reference standard or intermediate in the R&D of novel peptide-based therapeutics targeting growth disorders.
• Signal Transduction Research: Employed to map specific domains of IGF-1 involved in intracellular signaling cascades.
• Biochemical Reagent: Utilized in competitive binding assays (e.g., ELISA, RIA) and other analytical methods to quantify IGF-1 activity.

Basic Information

Product Name	Insulin Like Growth Factor I (1-27)-Gly-Gly-Gly-Gly-(38-70)
CAS No.	131595-85-2
Molecular Formula	C294H462N84O89S7
Molecular Weight	~6680.7 g/mol
Synonyms	IGF-I (1-27)-Gly4-(38-70); IGF-1 Fragment; Insulin-like Growth Factor I Fragment; Long-R3-IGF-I analog fragment; Somatomedin C fragment; IGF-I (1-27)-tetraglycine-(38-70); Recombinant IGF-I peptide fragment
EINECS	Contact for details

Quality Control

Our Insulin Like Growth Factor I (1-27)-Gly-Gly-Gly-Gly-(38-70) is produced under stringent conditions to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation. A detailed Certificate of Analysis (COA) providing full specifications and test results is available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.