Description

Boc-D-Dab(Fmoc)-Oh is a high-purity, orthogonally protected amino acid derivative essential for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise control over side-chain functionality during solid-phase and solution-phase peptide assembly. It is primarily utilized by the pharmaceutical, biotechnology, and life sciences industries for the development of novel therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key building block for the controlled incorporation of diaminobutyric acid (Dab) residues with orthogonal side-chain protection (Fmoc) and N-terminal protection (Boc).
• Solution-Phase Peptide Synthesis: Enables the synthesis of complex peptide sequences and cyclic peptides in solution, offering flexibility in coupling strategies.
• Pharmaceutical Research: Used in the research and development of peptide-based drugs, including antimicrobial peptides, hormone analogs, and targeted therapeutics.
• Peptidomimetic Design: Facilitates the creation of modified peptide structures with enhanced stability, bioavailability, or biological activity.
• Bioconjugation: Acts as a precursor for creating labeled peptides or peptide-protein conjugates for diagnostic and research applications.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify new bioactive peptide leads.

Basic Information

Item	Detail
Product Name	Boc-D-Dab(Fmoc)-Oh
CAS No.	131570-57-5
Molecular Formula	C25H30N2O6
Molecular Weight	454.52 g/mol
Synonyms	N-α-(tert-Butoxycarbonyl)-N-δ-(9-fluorenylmethoxycarbonyl)-D-2,4-diaminobutyric acid; Boc-D-Dab(Fmoc)-OH; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-((tert-butoxycarbonyl)amino)butanoic acid; Fmoc-D-Dab(Boc)-OH; Boc-D-2,4-diaminobutyric acid(Fmoc)-OH; D-Dab(Boc,Fmoc)-OH; Boc-D-Dab(Fmoc)-OH CAS 131570-57-5
EINECS	Contact for details

Quality Control

Our Boc-D-Dab(Fmoc)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.