Description

3-[(4-Methylpiperazino)Methyl]Benzoic Acid (4,5-Dihydro-4-Oxo-1H-Pyrazolo[3,4-D]Pyrimidine-1-Yl)Methyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is valued for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting specific enzymatic pathways. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel therapeutic agents. The material is supplied with stringent quality control to ensure batch-to-batch consistency for critical synthetic applications.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of targeted drug candidates, especially in oncology and antiviral research.
• Biochemical Research: Used as a reference standard or a probe molecule in enzymatic studies and structure-activity relationship (SAR) investigations.
• API Development: Integral to the process development and scale-up of new chemical entities (NCEs) requiring its specific fused heterocyclic core structure.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry projects and the development of novel synthetic methodologies.

Basic Information

Product Name	3-[(4-Methylpiperazino)Methyl]Benzoic Acid (4,5-Dihydro-4-Oxo-1H-Pyrazolo[3,4-D]Pyrimidine-1-Yl)Methyl Ester
CAS No.	131402-50-1
Molecular Formula	C20H23N5O3
Molecular Weight	381.43 g/mol
Synonyms	1H-Pyrazolo[3,4-d]pyrimidin-4(5H)-one, 1-[[[3-[(4-methyl-1-piperazinyl)methyl]phenyl]carbonyl]oxy]methyl]-; (4,5-Dihydro-4-oxo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl 3-[(4-methylpiperazin-1-yl)methyl]benzoate; 3-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid (4,5-Dihydro-4-oxo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl Ester; 1-[[[3-[(4-Methyl-1-piperazinyl)methyl]benzoyl]oxy]methyl]-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
EINECS	Contact for details

Quality Control

Our 3-[(4-Methylpiperazino)Methyl]Benzoic Acid (4,5-Dihydro-4-Oxo-1H-Pyrazolo[3,4-D]Pyrimidine-1-Yl)Methyl Ester is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.