Description

4-(2,2,2-Trifluoroethyl)Aniline is a specialized aromatic amine building block featuring a trifluoroethyl substituent, offering unique electronic and steric properties for advanced synthesis. This compound is valued for its role in introducing fluorine-containing motifs, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoroethyl group enhances biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorine-containing compounds for electronic display and lighting applications.
• Functional Material Development: Employed in creating specialty polymers, dyes, and ligands for catalysis that require specific fluorine-based properties.
• Organic Synthesis Research: A versatile reagent for academic and industrial research in novel fluorination reactions and heterocyclic chemistry.

Basic Information

Product Name	4-(2,2,2-Trifluoroethyl)Aniline
CAS No.	131395-17-0
Molecular Formula	C8H8F3N
Molecular Weight	175.15 g/mol
Synonyms	4-(2,2,2-Trifluoroethyl)benzenamine; 4-(Trifluoroethyl)aniline; 1-(4-Aminophenyl)-2,2,2-trifluoroethane; p-(Trifluoroethyl)aniline; Benzenamine, 4-(2,2,2-trifluoroethyl)-; 4-Aminobenzotrifluoride (less common); 4-(Trifluoroethyl)phenylamine
EINECS	Contact for details

Quality Control

Our 4-(2,2,2-Trifluoroethyl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.