Description

Tyr-Acth (4-10) CAS NO 131374-17-9 is a synthetic peptide fragment derived from the adrenocorticotropic hormone (ACTH) sequence, specifically encompassing amino acids 4 through 10. This compound is of significant interest for its role in neurological and immunological research, serving as a key tool for studying receptor interactions and signal transduction pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on neuropeptide and peptide-based therapeutic development.

Application

• Neuroscience Research: Investigation of ACTH receptor binding, neuronal signaling, and behavioral studies.
• Immunology Studies: Exploration of the immunomodulatory effects of ACTH-derived peptides.
• Pharmaceutical Development: Used as a reference standard or intermediate in the development of peptide-based drugs targeting neurological disorders.
• Biochemical Assays: Serves as a substrate or ligand in enzyme-linked immunosorbent assays (ELISA) and receptor binding assays.
• Academic Research: Fundamental research into peptide structure-activity relationships (SAR) and hormone fragment pharmacology.

Basic Information

Product Name	Tyr-Acth (4-10)
CAS No.	131374-17-9
Molecular Formula	C44H62N12O12S
Molecular Weight	959.1 g/mol
Synonyms	ACTH (4-10), Tyr-ACTH (4-10); Adrenocorticotropic Hormone Fragment 4-10 (Tyr-substituted); H-Tyr-Met-Glu-His-Phe-Arg-Trp-OH; [Tyr0]-ACTH (4-10); ACTH (human) (4-10) (Tyr0); Melanotropin potentiating factor fragment
EINECS	Contact for details

Quality Control

Our Tyr-Acth (4-10) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, mass spectrometry for identity confirmation, and amino acid analysis. We ensure compliance with relevant standards for research-grade peptides. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.