Description

(2S,3S)-2-Amino-3-Ethoxybutanoic Acid CAS NO 131234-99-6 is a high-purity, non-proteinogenic amino acid derivative characterized by its specific stereochemistry. This compound is a critical chiral building block in the synthesis of complex pharmaceuticals and bioactive molecules, where its defined stereocenter ensures the desired biological activity and efficacy. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of peptide-based drugs, enzyme inhibitors, and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in peptide and peptidomimetic drug development.
• Protease Inhibitor Research: Used in the design and construction of novel inhibitors targeting specific proteases for therapeutic applications.
• Peptide Chemistry: Serves as a specialized, stereochemically-defined amino acid residue in solid-phase and solution-phase peptide synthesis.
• Biochemical Research: Employed as a tool compound in enzymatic studies and for investigating structure-activity relationships (SAR).
• Agrochemical Synthesis: Potential intermediate in the creation of chiral, biologically active compounds for crop protection.
• Asymmetric Synthesis Catalyst Ligand: Can be utilized in the development of chiral ligands or organocatalysts for asymmetric transformations.

Basic Information

Product Name	(2S,3S)-2-Amino-3-Ethoxybutanoic Acid
CAS No.	131234-99-6
Molecular Formula	C6H13NO3
Molecular Weight	147.17 g/mol
Synonyms	(2S,3S)-2-Amino-3-ethoxybutanoic acid; L-threo-3-Ethoxyaspartic acid; 3-Ethoxy-D-aspartic acid; 2-Amino-3-ethoxybutanedioic acid (stereospecific); Ethoxyaspartate; Aminoethoxybutanoic acid; (2S,3S)-AEEA; CAS 131234-99-6
EINECS	Contact for details

Quality Control

Our (2S,3S)-2-Amino-3-Ethoxybutanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% de
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.