Description

H-Val-Thr-Cys-Gly-Oh CAS NO 131204-46-1 is a synthetic tetrapeptide sequence composed of L-Valine, L-Threonine, L-Cysteine, and Glycine, featuring a free C-terminal carboxylic acid. This compound serves as a critical building block in peptide synthesis and pharmaceutical research, offering a defined sequence for studying structure-activity relationships. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for drug discovery and development applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of more complex therapeutic peptides and peptidomimetics.
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies and proteomics research.
• Drug Discovery: Employed in high-throughput screening and structure-based drug design to develop novel bioactive compounds.
• Peptide Library Construction: Serves as a defined sequence unit for the solid-phase synthesis of combinatorial peptide libraries.
• Conjugation Chemistry: The cysteine residue provides a thiol group for site-specific conjugation with other molecules, such as linkers, fluorophores, or polymers.
• Cosmetic Peptide Development: Investigated for potential applications in advanced skincare formulations targeting specific biological pathways.

Basic Information

Product Name	H-Val-Thr-Cys-Gly-Oh
CAS No.	131204-46-1
Molecular Formula	C15H26N4O7S
Molecular Weight	406.45 g/mol
Synonyms	Val-Thr-Cys-Gly-OH; VTCG; L-Valyl-L-threonyl-L-cysteinylglycine; Tetrapeptide VTCG; H-Val-Thr-Cys-Gly-OH; H-Val-Thr-Cys-Gly; Glycine, L-valyl-L-threonyl-L-cysteinyl-; (4R)-4-[[(2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-5-[[(2S)-2-amino-2-carboxyethyl]sulfanyl]-5-oxopentanoic acid
EINECS	Contact for details

Quality Control

Our H-Val-Thr-Cys-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) detailing specific batch results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥95.0%
Single Impurity (HPLC)	≤1.0%
Water Content (KF)	≤5.0%
Peptide Content	≥80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.