Description

Hirullin P18 CAS NO 131158-67-3 is a synthetic peptide thrombin inhibitor, representing a high-purity, research-grade chemical standard. This compound is critical for biochemical research and pharmaceutical development, particularly in studies of blood coagulation pathways and antithrombotic drug discovery. It is an essential reagent for researchers and manufacturers in the fields of hemostasis, cardiovascular disease research, and diagnostic assay development.

Application

• Biochemical Research: As a specific and potent inhibitor of thrombin for in vitro enzymatic studies and mechanism-of-action investigations.
• Pharmaceutical Development: Serving as a reference standard or active pharmaceutical ingredient (API) intermediate in the development of novel anticoagulant and antithrombotic therapies.
• Diagnostic Reagents: Used in the formulation of control materials and calibrators for clinical coagulation testing kits and instruments.
• Protease Inhibition Studies: A key tool for studying serine protease activity, specificity, and inhibition kinetics in various biological systems.
• Academic & Institutional Labs: Fundamental research into cardiovascular diseases, thrombosis, and hemostasis at universities and research institutes.

Basic Information

Product Name	Hirullin P18
CAS No.	131158-67-3
Molecular Formula	C95H138N26O33
Molecular Weight	2152.3 g/mol
Synonyms	Hirullin P-18; D-Phe-Pro-Arg-Pro-(Gly)4-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu; Hirullin peptide P18; Thrombin inhibitor peptide P18; H-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH; (D-Phe)-Pro-Arg-Pro-(Gly)4-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu
EINECS	Contact for details

Quality Control

Our Hirullin P18 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.