Description

Benzenethiol, 2-Amino-3,4-Difluoro- (9Ci) is a specialized aromatic thiol derivative, distinguished by its amino and difluoro substituents, which impart unique reactivity and electronic properties. This compound serves as a critical high-value building block in advanced organic synthesis, enabling the precise construction of complex molecular architectures. It is primarily required by R&D and production teams in the pharmaceutical and agrochemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used to construct novel herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a versatile ligand for metal complexes in catalysis, leveraging the sulfur and nitrogen donor atoms.
• Material Science Research: Employed in the development of advanced polymers and electronic materials requiring specific thiol-ene chemistry.
• Chemical Biology Probes: Utilized for creating site-specific labeling reagents and protein modification tools due to its reactive thiol group.
• Fine Chemical Production: Acts as a building block for synthesizing dyes, pigments, and other specialty chemicals.

Basic Information

Product Name	Benzenethiol, 2-Amino-3,4-Difluoro- (9Ci)
CAS No.	131105-92-5
Molecular Formula	C6H5F2NS
Molecular Weight	161.17 g/mol
Synonyms	2-Amino-3,4-difluorobenzenethiol; 3,4-Difluoro-2-aminobenzenethiol; 2-Amino-3,4-difluorothiophenol; 2-Amino-3,4-difluorophenyl mercaptan; 131105-92-5; 2-Amino-3,4-difluorobenzene-1-thiol
EINECS	Contact for details

Quality Control

Our production of Benzenethiol, 2-Amino-3,4-Difluoro- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is characterized by advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support cGMP manufacturing standards for pharmaceutical customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and oxidation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.