Description

2-Amino-4-Fluorobenzenethiol is a versatile aromatic thiol derivative featuring both an amino and a fluorine substituent, making it a valuable bifunctional building block in advanced organic synthesis. Its unique structure provides critical reactivity for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), liquid crystal materials, and specialized ligands for catalysis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a chelating agent for creating metal complexes used in homogeneous catalysis and material science.
• Functional Material Production: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A valuable reagent for exploring new organic reactions and constructing heterocyclic compounds like benzothiazoles.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing sulfur-containing dyes and functional colorants.

Basic Information

Product Name	2-Amino-4-Fluorobenzenethiol
CAS No.	131105-89-0
Molecular Formula	C6H6FNS
Molecular Weight	143.18 g/mol
Synonyms	4-Fluoro-2-aminobenzenethiol; 2-Amino-4-fluorothiophenol; 4-Fluoro-2-aminothiophenol; 2-Amino-4-fluorophenyl mercaptan; 4-Fluoro-o-aminothiophenol; Benzenethiol, 2-amino-4-fluoro-; 2-Amino-4-fluorobenzene-1-thiol
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Fluorobenzenethiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation and light, minimize exposure to air and direct light during handling.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.