Description

cis-(1S,2S)-1,2-Dihydro-3-Fluorocatechol is a high-purity, chiral fluorinated catechol derivative, serving as a critical synthetic intermediate in advanced organic synthesis. Its value lies in its unique stereochemistry and fluorine atom, which are essential for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides where the fluorine moiety enhances efficacy and environmental stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored electronic properties.
• Chemical Biology Probes: Useful for creating fluorinated molecular probes to study enzyme mechanisms and biological pathways.

Basic Information

Product Name	cis-(1S,2S)-1,2-Dihydro-3-Fluorocatechol
CAS No.	131101-27-4
Molecular Formula	C6H5FO2
Molecular Weight	128.10 g/mol
Synonyms	(1S,2S)-3-Fluoro-1,2-benzenediol; (1S,2S)-3-Fluorocatechol; 3-Fluorobenzene-1,2-diol, (1S,2S)-; 3-Fluoro-1,2-dihydroxybenzene, cis-(1S,2S)-; 3-Fluoropyrocatechol, (1S,2S)-; Fluorocatechol derivative; Chiral fluorocatechol
EINECS	Contact for details

Quality Control

Our cis-(1S,2S)-1,2-Dihydro-3-Fluorocatechol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and standard spectroscopic methods for identity confirmation, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.