Description

H-Val-Ala-Pro-Ser-Asp-Ser-Ile-Gln-Ala-Glu-Glu-Trp-Tyr-Phe-Gly-Lys-Ile-Thr-Arg-Arg-Glu-Oh CAS NO 131023-24-0 is a synthetic peptide sequence, also known as a fragment of the human growth hormone-releasing hormone (GHRH). This high-purity peptide is critical for research and development in life sciences, offering a reliable reference standard and building block for advanced studies. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on endocrinology, metabolic disorders, and peptide-based therapeutic discovery.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of growth hormone-related therapies.
• Biochemical Assay Development: Used as a precise antigen or standard in immunoassays (ELISA, RIA) to study growth hormone secretion and regulation.
• Academic & Preclinical Studies: Essential for in vitro and in vivo research investigating the mechanisms of GHRH, somatostatin inhibition, and pituitary function.
• Peptide Synthesis & Conjugation: Acts as a starting material or fragment for the solid-phase or solution-phase synthesis of longer, modified peptide analogs.
• Quality Control & Analytical Standards: Provides a certified reference material for HPLC, MS, and other analytical methods to ensure batch consistency in peptide manufacturing.
• Drug Discovery Screening: Utilized in high-throughput screening (HTS) platforms to identify and validate novel compounds that modulate the GHRH receptor pathway.

Basic Information

Product Name	H-Val-Ala-Pro-Ser-Asp-Ser-Ile-Gln-Ala-Glu-Glu-Trp-Tyr-Phe-Gly-Lys-Ile-Thr-Arg-Arg-Glu-Oh
CAS No.	131023-24-0
Molecular Formula	C108H165N31O34
Molecular Weight	2386.68 g/mol
Synonyms	GHRH (1-29) amide, human; Growth Hormone-Releasing Hormone (1-29), human; Somatoliberin (1-29); hGHRH(1-29)NH2; GRF (1-29), human; Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2 (alternative sequence representation); Human growth hormone-releasing factor (1-29) amide
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry (MS) for identity confirmation. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting purity, amino acid analysis, and other critical parameters to ensure compliance with research-grade standards. Specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular weight confirmed by Mass Spectrometry
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Within ±10% of theoretical values
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.