Description

N(Epsilon)-(Carboxymethyl)Hydroxylysine is a chemically modified derivative of the amino acid hydroxylysine, featuring a carboxymethyl group on the ε-amino group. This specific modification is critical for research and development in advanced biochemical applications, particularly in the study of protein cross-links and advanced glycation end-products (AGEs). It is an essential analytical standard and building block for researchers and manufacturers in the life sciences, pharmaceutical development, and diagnostic sectors requiring high-purity, well-characterized compounds.

Application

• Biochemical Research Standard: Serves as a critical reference standard in mass spectrometry and chromatography for the identification and quantification of protein glycation and cross-linking products.
• Pharmaceutical R&D: Used as a key intermediate or analytical marker in the development of therapeutics targeting diabetes complications, aging, and diseases related to collagen abnormalities.
• Diagnostic Kit Development: Employed in the calibration and validation of diagnostic assays designed to measure specific AGEs in biological samples (e.g., serum, tissue).
• Nutritional Science Studies: Utilized as a precise marker in research investigating the metabolic fate and health impacts of dietary Maillard reaction products.
• Material Science: Investigated for potential use in the synthesis of novel bio-inspired polymers and hydrogels due to its reactive functional groups.

Basic Information

Product Name	N(Epsilon)-(Carboxymethyl)Hydroxylysine
CAS No.	130985-18-1
Molecular Formula	C8H16N2O5
Molecular Weight	220.22 g/mol
Synonyms	Nε-(Carboxymethyl)hydroxylysine; CM-HL; N6-Carboxymethylhydroxylysine; (2S,5R)-2-Amino-6-[(carboxymethyl)amino]-5-hydroxyhexanoic acid; Nε-Carboxymethylhydroxylysine; Hydroxylysine-Carboxymethyl; AGE-HL; Carboxymethyl Hydroxylysine
EINECS	Contact for details

Quality Control

Every batch of N(Epsilon)-(Carboxymethyl)Hydroxylysine is produced and analyzed under a strict quality management system. We provide comprehensive analytical documentation to ensure traceability and reliability for your critical research and production needs. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and conformity to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is kept sealed in a dry environment to prevent absorption of water vapor.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.