Description

Lys8-Conopressin S CAS NO 130836-26-9 is a synthetic analog of the neurohypophysial hormone conopressin, specifically modified with a lysine substitution at position 8. This compound is of significant interest in biochemical and pharmacological research due to its specific receptor binding affinity and potential as a tool for studying vasopressin/oxytocin receptor systems. It is primarily utilized by research institutions and pharmaceutical development laboratories engaged in neuroscience, peptide hormone research, and drug discovery programs.

Application

• Neuroscience Research: As a selective ligand for studying the structure, function, and distribution of vasopressin and oxytocin receptor subtypes in the central nervous system.
• Pharmacological Profiling: Used in in vitro assays to evaluate agonist/antagonist activity, receptor binding kinetics, and signal transduction pathways.
• Drug Discovery: Serves as a reference standard or a lead compound in the development of novel therapeutics targeting disorders related to social behavior, stress, and fluid balance.
• Biochemical Studies: Employed in investigations of peptide-receptor interactions, G-protein coupling, and the design of peptide analogs with enhanced stability or specificity.
• Academic Research: A key reagent for university and institutional labs focusing on endocrinology, behavioral pharmacology, and comparative physiology.

Basic Information

Product Name	Lys8-Conopressin S
CAS No.	130836-26-9
Molecular Formula	C₄₆H₆₈N₁₄O₁₂S₂
Molecular Weight	1081.3 g/mol
Synonyms	[Lys8]-Conopressin S; Lysipressin; Conopressin S (Lys8 analog); CFIRNCPKG-NH2 (Lys8); Vasotocin analog; [8-Lysine]-conopressin S; Cone Snail Peptide Analog
EINECS	Contact for details

Quality Control

Our Lys8-Conopressin S is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all test results against stringent in-house specifications to ensure consistency and reliability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a dry environment before opening to prevent condensation. Aliquot into single-use vials to minimize repeated freeze-thaw cycles and exposure to atmospheric oxygen.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by AAA)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.