Description

5-Oxo-L-Pro-1-(Ethoxycarbonyl)-L-His-L-Pro-Nh2 is a synthetic tripeptide derivative, specifically engineered for advanced research and development applications. This compound is valued for its role as a key intermediate in the synthesis of complex bioactive peptides and peptidomimetics, offering precise structural control. It is primarily utilized by pharmaceutical R&D teams, biotechnology firms, and academic research institutions focused on drug discovery, enzyme inhibitor studies, and novel therapeutic agent development.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in academic and industrial laboratories for studying enzyme-substrate interactions, receptor binding, and signal transduction pathways.
• Peptidomimetic Development: Serves as a core structure for designing and synthesizing peptidomimetics with enhanced stability and bioavailability.
• Protease Inhibitor Studies: Employed in the research and development of specific protease inhibitors due to its tailored amino acid sequence.
• High-Purity Reference Standard: Can be supplied as a characterized reference material for analytical method development and quality control in peptide manufacturing.

Basic Information

Product Name	5-Oxo-L-Pro-1-(Ethoxycarbonyl)-L-His-L-Pro-Nh2
CAS No.	130817-92-4
Molecular Formula	C20H28N6O7
Molecular Weight	464.47 g/mol
Synonyms	5-Oxo-L-prolyl-1-(ethoxycarbonyl)-L-histidyl-L-prolinamide; L-Histidine, L-prolinamide, 5-oxo-L-prolyl-1-(ethoxycarbonyl)-; 5-Oxo-Pro-1-(EtOCO)-His-Pro-NH2; (S)-2-((S)-1-((S)-5-Oxo-1-(ethoxycarbonyl)pyrrolidine-2-carboxamido)-3-(1H-imidazol-5-yl)propanamido)pyrrolidine-1-carboxamide; Fmoc-His(Trt)-Pro-NH2 related derivative; Peptide synthesis intermediate 130817-92-4
EINECS	Contact for details

Quality Control

Our 5-Oxo-L-Pro-1-(Ethoxycarbonyl)-L-His-L-Pro-Nh2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC-MS)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.