Description

Bombesin (6-13), Phe(6) Methyl Ester is a synthetic peptide fragment derived from the C-terminal region of the bombesin peptide. This compound is a valuable research-grade biochemical tool, specifically designed for its receptor-binding properties and stability. It is primarily utilized by researchers and pharmaceutical developers in the fields of oncology, neurobiology, and gastrointestinal physiology. The product is supplied as a high-purity material, essential for reliable and reproducible experimental results.

Application

• Biomedical Research: Used as a specific ligand in receptor binding assays and signal transduction studies related to gastrin-releasing peptide (GRP) receptors.
• Oncology Studies: Investigated for its role in tumor cell proliferation, particularly in cancers where bombesin-like peptides are implicated (e.g., small cell lung carcinoma, prostate cancer).
• Neuropharmacology: Serves as a tool compound to study the neurological effects and behavioral responses mediated by bombesin receptor subtypes.
• Drug Discovery & Development: Acts as a reference standard or a starting point for the design and synthesis of novel diagnostic agents or therapeutic candidates targeting bombesin receptors.
• In Vitro Diagnostics (IVD) Development: Employed in the development of immunoassays and other diagnostic tests to detect bombesin-related peptides or their receptors.

Basic Information

Product Name	Bombesin (6-13), Phe(6) Methyl Ester
CAS No.	130800-38-3
Molecular Formula	C46H68N14O11
Molecular Weight	969.1 g/mol
Synonyms	Bombesin (6-14), Phe(6) Methyl Ester; [Phe6, psi(CH2NH)Leu13]Bombesin(6-13) Methyl Ester; Bombesin Receptor Antagonist; H-Gln-Trp-Ala-Val-Gly-His-Pheψ(CH2NH)Leu-Met-NH2 Methyl Ester; BW2258U89; Pseudopeptide Bombesin Antagonist; GRP Receptor Antagonist
EINECS	Contact for details

Quality Control

Our Bombesin (6-13), Phe(6) Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports reproducible scientific outcomes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Amino Acid Composition	Conforms to theoretical values
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.