Description

[D-Lys6]-Lhrh is a synthetic peptide analog of Gonadotropin-Releasing Hormone (GnRH), specifically modified at the sixth position with a D-Lysine residue. This modification enhances its metabolic stability and receptor-binding affinity, making it a critical tool for advanced endocrinology research and therapeutic development. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on reproductive health, oncology, and peptide-based drug discovery.

Application

• Endocrinology Research: Used as a potent agonist in studies of the hypothalamic-pituitary-gonadal axis and hormone regulation mechanisms.
• Pharmaceutical Reference Standard: Serves as a high-purity analytical standard for quality control in the production of GnRH analog therapeutics.
• Drug Discovery & Development: A key intermediate or active pharmaceutical ingredient (API) in the development of novel treatments for hormone-dependent cancers (e.g., prostate cancer, breast cancer) and reproductive disorders.
• Biochemical Assays: Employed in receptor binding studies, signal transduction research, and in vitro bioactivity testing.
• Veterinary Medicine: Potential application in animal breeding programs and veterinary reproductive management.

Basic Information

Product Name	[D-Lys6]-Lhrh
CAS No.	130751-49-4
Molecular Formula	C₆₀H₈₆N₁₈O₁₃
Molecular Weight	1283.5 g/mol
Synonyms	Des-Gly10, D-Lys6-GnRH ethylamide; D-Lys6-Luteinizing Hormone-Releasing Hormone; D-Lys6-LHRH; Fertirelin Acetate (related analog); GnRH (6-D-Lysine) ethylamide; LHRH (6-D-Lys); Gonadorelin (6-D-Lys) analog; P-Glu-His-Trp-Ser-Tyr-D-Lys-Leu-Arg-Pro-NHEt
EINECS	Contact for details

Quality Control

Our [D-Lys6]-Lhrh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Acetate Content (HPLC)	5.0% - 12.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.