Description

Acetyl-Tryptophyl-Isoleucyl-Alanyl-Aminoisobutyryl-Isoleucyl-Valyl-Aminoisobutyryl-Leucyl-Aminoisobutyryl-Proline Methyl Ester is a synthetic peptide derivative of significant interest in advanced pharmaceutical research and development. This compound, with CAS number 130517-75-8, serves as a critical intermediate or reference standard for the synthesis and study of complex bioactive peptides. It is primarily needed by research institutions, pharmaceutical companies, and biotechnology firms engaged in peptide-based drug discovery, metabolic studies, and the development of novel therapeutic agents.

Application

• Pharmaceutical Research Intermediate: A key building block for the synthesis of complex peptide-based drug candidates targeting various diseases.
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies, receptor binding assays, and metabolic pathway analysis.
• Drug Discovery & Development: Serves as a core structure for developing novel therapeutic peptides with potential applications in oncology, endocrinology, and neurology.
• Proteomics & Peptide Chemistry: Employed in academic and industrial laboratories for studying peptide structure-activity relationships (SAR) and stability.
• High-Purity Reference Standard: Utilized in analytical method development and validation for quality control of peptide APIs (Active Pharmaceutical Ingredients).
• Custom Peptide Synthesis: Acts as a specialized starting material for contract research organizations (CROs) and CDMOs (Contract Development and Manufacturing Organizations) producing custom peptides.

Basic Information

Item	Details
Product Name	Acetyl-Tryptophyl-Isoleucyl-Alanyl-Aminoisobutyryl-Isoleucyl-Valyl-Aminoisobutyryl-Leucyl-Aminoisobutyryl-Proline Methyl Ester
CAS No.	130517-75-8
Molecular Formula	C58H91N13O13
Molecular Weight	1166.4 g/mol
Synonyms	Ac-Trp-Ile-Ala-Aib-Ile-Val-Aib-Leu-Aib-Pro-OMe; Ac-T-W-I-A-A-I-V-A-L-A-P-OMe; N-Acetyl-L-tryptophyl-L-isoleucyl-L-alanyl-2-aminoisobutyryl-L-isoleucyl-L-valyl-2-aminoisobutyryl-L-leucyl-2-aminoisobutyryl-L-proline methyl ester; Aib-containing peptide derivative; Methyl Ac-Trp-Ile-Ala-Aib-Ile-Val-Aib-Leu-Aib-Pro; Helix-inducing peptide analog; Peptide with α-aminoisobutyric acid residues
EINECS	Contact for details

Quality Control

Our Acetyl-Tryptophyl-Isoleucyl-Alanyl-Aminoisobutyryl-Isoleucyl-Valyl-Aminoisobutyryl-Leucyl-Aminoisobutyryl-Proline Methyl Ester is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere at lower temperatures (e.g., -20°C).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.