Description

1-{7-[(E)-2-(Dimethylamino)Vinyl]Pyrazolo-[1,5-A]Pyrimidin-6-Yl}Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyrazolopyrimidine core. This compound matters for its critical role as a key building block in the synthesis of novel, targeted therapeutic agents, offering researchers a reliable and well-defined starting material. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of investigational drug candidates, particularly in oncology and anti-inflammatory research.
• Kinase Inhibitor Development: Serves as a core scaffold for creating potent and selective inhibitors targeting specific protein kinases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize drug-like properties and efficacy.
• Biochemical Probe Synthesis: Employed to create labeled or modified compounds for studying biological pathways and target engagement.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines.
• Academic Research: Utilized in university and institutional labs for pioneering research in heterocyclic chemistry and drug design.

Basic Information

Product Name	1-{7-[(E)-2-(Dimethylamino)Vinyl]Pyrazolo-[1,5-A]Pyrimidin-6-Yl}Ethanone
CAS No.	130506-81-9
Molecular Formula	C₁₂H₁₄N₄O
Molecular Weight	230.26 g/mol
Synonyms	1-[7-[(E)-2-(Dimethylamino)ethenyl]pyrazolo[1,5-a]pyrimidin-6-yl]ethanone; 6-Acetyl-7-[(E)-2-(dimethylamino)vinyl]pyrazolo[1,5-a]pyrimidine; 130506-81-9; Ethanone, 1-[7-[(E)-2-(dimethylamino)ethenyl]pyrazolo[1,5-a]pyrimidin-6-yl]-; Pyrazolo[1,5-a]pyrimidine-6-acetic acid derivative; DMAPVP intermediate
EINECS	Contact for details

Quality Control

Our production of 1-{7-[(E)-2-(Dimethylamino)Vinyl]Pyrazolo-[1,5-A]Pyrimidin-6-Yl}Ethanone adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with exacting R&D and pre-clinical standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.