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Farnesylleucyl-Alanyl-Arginyl-Tyrosyl-Lysyl-Cysteine CAS NO 130447-82-4
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CAS No.:130447-82-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Farnesylleucyl-Alanyl-Arginyl-Tyrosyl-Lysyl-Cysteine is a synthetic peptide sequence of significant interest in biochemical research and pharmaceutical development. This compound matters due to its role as a potential precursor or intermediate in the study of protein prenylation, a critical post-translational modification involved in cell signaling and regulation. It is primarily needed by research institutions and biotechnology companies focused on oncology, metabolic disorders, and the development of novel therapeutic agents targeting specific enzymatic pathways.
Application
- Biochemical Research: Used as a critical substrate or inhibitor in enzymatic assays to study farnesyltransferase and related prenylation enzymes.
- Pharmaceutical R&D: Serves as a key intermediate in the synthesis and development of novel drug candidates targeting Ras oncoproteins and other prenylated proteins.
- Proteomics & Signal Transduction Studies: Employed to investigate the mechanisms of cell membrane localization and the function of lipid-modified peptides in cellular communication.
- Reference Standard: Utilized as a high-purity analytical standard for method development and quality control in peptide synthesis and characterization.
- Academic Research: Applied in university laboratories for fundamental studies on protein chemistry, post-translational modifications, and their implications in disease.
Basic Information
| Product Name | Farnesylleucyl-Alanyl-Arginyl-Tyrosyl-Lysyl-Cysteine |
| CAS No. | 130447-82-4 |
| Molecular Formula | C52H86N12O10S |
| Molecular Weight | 1047.4 g/mol |
| Synonyms | Farnesyl-LARKYC; Farnesyl-Leu-Ala-Arg-Tyr-Lys-Cys; Prenylated LARKYC peptide; N-[(2E,6E)-3,7,11-Trimethyldodeca-2,6,10-trien-1-yl]-L-leucyl-L-alanyl-L-arginyl-L-tyrosyl-L-lysyl-L-cysteine; L-Leucine, N-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]-, L-alanyl-L-arginyl-L-tyrosyl-L-lysyl-L-cysteine; Farnesyl peptide inhibitor; FTase substrate analog |
| EINECS | Contact for details |
Quality Control
Our Farnesylleucyl-Alanyl-Arginyl-Tyrosyl-Lysyl-Cysteine is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results to ensure compliance with your research and development requirements.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC/MS) | Conforms |
| Purity (HPLC) | ≥ 95.0% |
| Single Impurity (HPLC) | ≤ 1.0% |
| Water Content (KF) | ≤ 5.0% |
| Peptide Content | ≥ 80.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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