Description

Benzenemethanamine, 3,5-Difluoro-α,α-Dimethyl- is a high-value fluorinated aromatic amine building block, distinguished by its dimethyl-substituted benzylic amine and difluoro substitution pattern. This structure offers unique electronic and steric properties, making it a critical intermediate for the synthesis of advanced pharmaceutical and agrochemical compounds. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing complex molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs, kinase inhibitors, and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the fluorine atoms and amine group contribute to efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and fluorinated nature.
• Chemical Biology & Proteomics: Utilized as a building block for fluorescent probes, affinity tags, and other molecular tools.

Basic Information

Product Name	Benzenemethanamine, 3,5-Difluoro-α,α-Dimethyl-
CAS No.	130416-51-2
Molecular Formula	C9H11F2N
Molecular Weight	171.19 g/mol
Synonyms	3,5-Difluoro-α,α-dimethylbenzylamine; (3,5-Difluorophenyl)dimethylmethanamine; α,α-Dimethyl-3,5-difluorobenzylamine; 1-(3,5-Difluorophenyl)-N,N-dimethylmethanamine; 3,5-Difluoro-α-methylbenzenemethanamine; Benzenemethanamine, α,α-dimethyl-3,5-difluoro-; (3,5-Difluorobenzyl)dimethylamine
EINECS	Contact for details

Quality Control

Our Benzenemethanamine, 3,5-Difluoro-α,α-Dimethyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our production adheres to cGMP guidelines where applicable, ensuring consistency and reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids, strong oxidizing agents, and moisture. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.