Description

Geranylgeranylcysteine Methyl Ester is a specialized, high-purity biochemical intermediate crucial for advanced research and synthesis. This compound matters as a key building block in the study of protein prenylation, a vital post-translational modification process. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on signal transduction pathways, cancer research, and metabolic studies.

Application

• Biochemical Research: A critical precursor and reference standard in the study of protein prenylation mechanisms, particularly for Rab GTPases.
• Pharmaceutical Development: Serves as a key intermediate in the synthesis of novel therapeutic agents targeting prenylation-dependent diseases.
• Enzymology Studies: Used as a substrate or inhibitor in assays for enzymes involved in lipid modification pathways, such as prenyltransferases.
• Cell Signaling Research: Employed to investigate the role of geranylgeranylated proteins in intracellular trafficking, proliferation, and apoptosis.
• Metabolic Pathway Analysis: A tool for probing isoprenoid biosynthesis and its connection to cholesterol metabolism and related disorders.
• Academic & Discovery Chemistry: Used in synthetic organic chemistry to create analogs for structure-activity relationship (SAR) studies.

Basic Information

Product Name	Geranylgeranylcysteine Methyl Ester
CAS No.	130413-80-8
Molecular Formula	C25H41NO2S
Molecular Weight	419.67 g/mol
Synonyms	GG-Cys-OMe; Geranylgeranyl-L-cysteine methyl ester; (2R)-2-Amino-3-[[(2E,6E,10E)-3,7,11,15-Tetramethylhexadeca-2,6,10,14-tetraen-1-yl]sulfanyl]propanoic acid methyl ester; L-Cysteine, S-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraen-1-yl)-, methyl ester; Methyl S-geranylgeranyl-L-cysteinate; Prenylcysteine methyl ester analog
EINECS	Contact for details

Quality Control

Our Geranylgeranylcysteine Methyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation via NMR and mass spectrometry. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. Allow the vial to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.