Description

n-tert-Butyloxycarbonyl-Valyl-Alanyl-Leucyl-Aminoisobutyryl-Valyl-Alanyl-Leucyl(Valyl-Alanyl-Leucyl-Aminoisobutyryl)(2) Methyl Ester is a complex, custom-designed synthetic peptide derivative, serving as a critical building block in advanced pharmaceutical research. Its precise sequence and protective groups make it an essential intermediate for the development of novel therapeutic peptides and peptidomimetics. This high-purity compound is primarily utilized by research institutions and pharmaceutical companies focused on drug discovery, particularly in oncology, metabolic disorders, and antimicrobial applications.

Application

• Pharmaceutical Intermediate: A key precursor in the solid-phase or solution-phase synthesis of complex therapeutic peptide candidates.
• Drug Discovery Research: Used in structure-activity relationship (SAR) studies to optimize peptide stability, bioavailability, and target binding affinity.
• Peptidomimetic Development: Serves as a scaffold for creating non-natural peptide analogs with enhanced metabolic stability and pharmacological properties.
• Bioconjugation: The reactive terminal and side-chain functionalities can be utilized for conjugation with other molecules, such as dyes, polymers, or drug delivery carriers.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in peptide manufacturing.

Basic Information

Product Name	n-tert-Butyloxycarbonyl-Valyl-Alanyl-Leucyl-Aminoisobutyryl-Valyl-Alanyl-Leucyl(Valyl-Alanyl-Leucyl-Aminoisobutyryl)(2) Methyl Ester
CAS No.	130378-94-8
Molecular Formula	C68H118N12O19
Molecular Weight	1383.73 g/mol
Synonyms	Boc-Val-Ala-Leu-Aib-Val-Ala-Leu(Val-Ala-Leu-Aib)2-OMe; Boc-V-A-L-Aib-V-A-L-(V-A-L-Aib)2-OMe; (2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-methylbutanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]-3,3-dimethyl-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-methylbutanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoyl]-N-[(1S)-3-methyl-1-[[(2S)-1-methoxy-3-methyl-1-oxobutan-2-yl]carbamoyl]butyl]butanamide; Custom Peptide 130378-94-8; Aib-containing Peptide Ester; Boc-protected Peptide Fragment
EINECS	Contact for details

Quality Control

This product is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each batch is accompanied by comprehensive analytical data, including HPLC purity, mass spectrometry (MS) confirmation, and chiral purity verification. Certificates of Analysis (COA) detailing all specifications are available upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This compound is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.