Description

7-S-Glutathionyltryptamine-4,5-Dione is a specialized biochemical compound formed by the conjugation of tryptamine-4,5-dione with the tripeptide glutathione. This molecule is of significant interest in advanced biochemical research, particularly in the study of oxidative stress pathways, neurochemistry, and the metabolism of indole derivatives. It serves as a critical reference standard and intermediate for researchers and developers in the pharmaceutical and life sciences sectors, enabling the investigation of novel therapeutic targets and diagnostic markers.

Application

• Biochemical Research: Used as a high-purity reference standard in studies of oxidative stress, redox biology, and glutathione metabolism.
• Pharmaceutical Development: Serves as a key intermediate or analytical standard in the research and development of neuroprotective agents or compounds targeting oxidative damage.
• Metabolite Studies: Employed in the identification and quantification of tryptamine-derived metabolites in complex biological matrices.
• Enzymology: Acts as a substrate or inhibitor in enzymatic assays to study the activity of glutathione S-transferases (GSTs) or other related enzymes.
• Analytical Chemistry: Utilized for method development and validation in advanced chromatographic (HPLC, LC-MS) techniques within contract research organizations (CROs) and quality control labs.

Basic Information

Product Name	7-S-Glutathionyltryptamine-4,5-Dione
CAS No.	130369-71-0
Molecular Formula	C20H24N6O7S
Molecular Weight	492.50 g/mol
Synonyms	Glutathionyltryptaminequinone; 7-(Glutathion-S-yl)tryptamine-4,5-dione; Tryptamine-4,5-dione glutathione adduct; GST-Dione; 5-(2-Aminoethyl)-2-(1-((carboxymethyl)carbamoyl)-2-((1-((carboxy)methyl)amino)-1-oxo-3-((4-oxo-5-(2-sulfanylethyl)-2,3,4,5-tetrahydro-1H-pyrrol-3-yl)amino)-3-oxopropyl)disulfaneyl)ethyl)-1H-indole-3,7-dione; Glutathione conjugate of tryptamine-4,5-dione
EINECS	Contact for details

Quality Control

Our 7-S-Glutathionyltryptamine-4,5-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.