Description

Glyceraldehyde 3-Phosphate Dehydrogenase (304-313) is a synthetic peptide fragment corresponding to amino acid residues 304-313 of the human GAPDH enzyme, with CAS Number 130349-12-1. This high-purity peptide is a critical research tool for studying enzyme function, protein-protein interactions, and antibody development. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in metabolic pathway analysis, immunology, and diagnostic assay development.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate the catalytic mechanism and kinetics of Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH).
• Antibody Production & Epitope Mapping: Serves as a specific immunogen for generating monoclonal or polyclonal antibodies targeting the GAPDH protein, facilitating Western blot, ELISA, and immunohistochemistry applications.
• Protein Interaction Studies: Employed in pull-down assays, surface plasmon resonance (SPR), and other biophysical techniques to identify and characterize binding partners of the GAPDH enzyme.
• Diagnostic Development: Acts as a key component in the development of immunoassays and diagnostic kits for diseases where GAPDH expression or activity is a biomarker.
• Cell Signaling & Apoptosis Research: Investigated for its non-glycolytic functions, including roles in apoptosis, DNA repair, and transcriptional regulation within cellular nuclei.
• Quality Control Standard: Used as a reference standard in pharmaceutical and biotechnology quality control laboratories to ensure assay consistency and specificity.

Basic Information

Product Name	Glyceraldehyde 3-Phosphate Dehydrogenase (304-313)
CAS No.	130349-12-1
Molecular Formula	C48H78N14O17S
Molecular Weight	1131.3 g/mol
Synonyms	GAPDH (304-313); Glyceraldehyde-3-phosphate dehydrogenase peptide (304-313); Human GAPDH residues 304-313; KVKVVGINGFG; GAPDH epitope peptide; Glyceraldehyde-3-phosphate dehydrogenase fragment; G3P dehydrogenase peptide; EC 1.2.1.12 peptide fragment
EINECS	Contact for details

Quality Control

Our Glyceraldehyde 3-Phosphate Dehydrogenase (304-313) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry (MS) for identity confirmation. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, ensuring compliance with research-grade standards. Specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. For optimal performance, prepare aliquots to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Sequence	KVKVVGINGFG
Molecular Weight	1131.3 ± 1.0 Da
Solubility	Soluble in water or dilute aqueous acetic acid
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.