Description

Fmoc-Asp(Ochex)-Oh is a protected amino acid derivative, specifically an Fmoc-protected aspartic acid with a cyclohexyl ester side chain. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled incorporation of aspartic acid while preventing unwanted side reactions. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing therapeutic peptides, diagnostic agents, and complex biomolecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential assembly of peptide chains on resin.
• Pharmaceutical Research: Synthesis of peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Bioconjugation: Used in the preparation of peptide-protein or peptide-small molecule conjugates for targeted therapies.
• Combinatorial Chemistry: Serves as a building block in libraries for high-throughput screening of bioactive compounds.
• Academic & Industrial R&D: Fundamental research in biochemistry, medicinal chemistry, and molecular biology.
• Production of Custom Peptides: For use in diagnostics, vaccines, and cosmetic active ingredients.

Basic Information

Product Name	Fmoc-Asp(Ochex)-Oh
CAS No.	130304-80-2
Molecular Formula	C25H27NO6
Molecular Weight	437.49 g/mol
Synonyms	Fmoc-L-aspartic acid 4-cyclohexyl ester; Fmoc-Asp(OcHex)-OH; N-(9-Fluorenylmethoxycarbonyl)-L-aspartic acid 4-cyclohexyl ester; Fmoc-Asp(Ocyclohexyl)-OH; Fmoc-Aspartyl(O-cyclohexyl)-OH; Nα-Fmoc-L-aspartic acid β-cyclohexyl ester; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)succinic acid 4-cyclohexyl ester
EINECS	Contact for details

Quality Control

Our Fmoc-Asp(Ochex)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.