Description

2-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)acetonitrile is a versatile and high-purity chemical intermediate of significant importance in advanced organic synthesis. Its core value lies in its functionalized pyrimidinone structure, which serves as a critical building block for constructing complex molecules with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel nucleoside analogs and heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral and anticancer agents, particularly as a scaffold for modified nucleosides and pyrimidine derivatives.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, leveraging its heterocyclic core for bioactivity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic systems and functionalized molecules.
• Bioconjugation & Probe Development: The reactive nitrile group allows for its use in creating biochemical probes and conjugates for diagnostic applications.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Item	Detail
Product Name	2-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)acetonitrile
CAS No.	130278-40-9
Molecular Formula	C7H5N3O2
Molecular Weight	163.14 g/mol
Synonyms	1-(Cyanomethyl)pyrimidine-2,4(1H,3H)-dione; 1-(Cyanomethyl)uracil; N-(Cyanomethyl)uracil; 2,4(1H,3H)-Pyrimidinedione, 1-(cyanomethyl)-; Uracil, 1-(cyanomethyl)-; 130278-40-9; Acetonitrile, 2-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-
EINECS	Contact for details

Quality Control

Our 2-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.